Functional Outcome After Mechanical Thrombectomy with or without Previous Thrombolysis
نویسندگان
چکیده
Introduction Combined intravenous therapy (IVT) and mechanical thrombectomy (MT) is the standard treatment for acute ischemic stroke (AIS) with large vessel occlusion (LVO). However, use of IVT before MT recently being questioned. Objectives To compare patients treated those alone, in a real-world scenario. Methods Retrospective analysis AIS LVO anterior circulation who underwent MT, or without previous IVT, between 2016 2018. Results A total 524 were included (347 submitted to IVT+MT; 177 alone). No differences groups found except higher time from onset CT groin puncture group (297.5 min vs 115.0 394.0 250.0 respectively, p < 0.001). Multivariable showed that age<75 years (OR 2.65, 95% CI 1.71–4.07, 0.001), not using antiplatelet 1.93, 1.21–3.08, = 0.006), low prestroke mRS 4.33, 1.89–9.89, initial NIHSS 0.89, 0.86–0.93, absent cerebral edema 7.83, 3.31–18.51, mTICI 2b/3 4.56, 2.17–9.59, 0.001) independently associated good outcome (mRS 0-2). Conclusions Our findings support idea does influence prognosis, setting.
منابع مشابه
Mechanical Thrombectomy Improves Functional Outcomes Independent of Pretreatment With Intravenous Thrombolysis.
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متن کاملResponse to Letter Regarding Article, "Mechanical Thrombectomy Improves Functional Outcomes Independent of Pretreatment With Intravenous Thrombolysis".
Response to Letter Regarding Article, “Mechanical Thrombectomy Improves Functional Outcomes Independent of Pretreatment With Intravenous Thrombolysis” We would like to thank Kamtchum-Tatuene et al for commenting on our recently published meta-analysis evaluating the potential interaction of pretreatment with intravenous thrombolysis (IVT) on the association of endovascular reperfusion therapies...
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متن کامل
Comparison of outcome and interventional complication rate in patients with acute stroke treated with mechanical thrombectomy with and without bridging thrombolysis.
BACKGROUND No randomized trial has investigated the effect of mechanical thrombectomy (MT) alone in patients with acute stroke. There are conflicting results as to whether prior intravenous thrombolysis (IVT) facilitates subsequent MT, and data in patients treated with MT alone owing to contraindications to IVT are limited. OBJECTIVE To compare consecutive patients treated with MT alone or wi...
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ژورنال
عنوان ژورنال: Journal of stroke and cerebrovascular diseases
سال: 2021
ISSN: ['1052-3057', '1532-8511']
DOI: https://doi.org/10.1016/j.jstrokecerebrovasdis.2020.105495